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- Medicine
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Lee, Ki-Young
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- thylee@skku.edu
- 031-299-6225
○ 주요 학력, 경력 (Experience)
▪ 충북대학교 이학사
▪ 충북대학교 약학석사
▪ 연세대학교 공학박사 (분자면역학)
▪ 예일대학교, 의과대학, Post-Doc.
▪ 성균관대학교, 의과대학, 조교수, 부교수, 교수
○ 연구분야(Research Field)
▪ Molecular mechanism of innate immunity mediated by Toll-Like Receptors (TLRs
▪ Autophagy regulation of innate immunity mediated by Toll-Like Receptors (TLRs)
▪ Humanized patient-derived xenograft (PDX) mice in Cancer immunity
○ 주요 연구논문(Major Research Achievements)
▪ Min Y, Kim MJ, Lee S, Chun E, Lee KY. Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation. Autophagy. 2018;14(8):1347-1358
▪ Min Y, Lee S, Kim MJ, Chun E, Lee KY. Ubiquitin-Specific Protease 14 Negatively Regulates Toll-Like Receptor 4-Mediated Signaling and Autophagy Induction by Inhibiting Ubiquitination of TAK1-Binding Protein 2 and Beclin 1. Front Immunol. 2017 Dec 15;8:1827
▪ Min Y, Wi SM, Kang JA, Yang T, Park CS, Park SG, Chung S, Shim JH, Chun E, Lee KY. Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6. Cell Death Dis. 2016 Jul 28;7(7):e2313
○ 연구협력 필요 분야(Research Interest)
▪Bioinformatics in Cancers
▪Drug development targeting cancers and inflammatory diseases
○ 연구협력 가능 분야(Research Collaboration)
▪ Drug screening platform in cancers and inflammatory diseases