○ 주요 학력, 경력 (Experience)
▪ 1990-2001 BS, MS, Ph.D. Department of Food Science and Biotechnology, Seoul National University.
▪ 2001-2003 Postdoctral Research Associate, Iowa State University
▪ 2003-2005 Assistant Professor, Andong National University, Korea
▪ 2006-Present Professor, Sungkyunkwan University, Korea
○ 연구분야(Research Field)
▪ Nanodisc technology and development of antiviral nanoperforator
▪ Protein engineering for improved solubility and stability, and microbial cell factory using the engineered proteins
▪ Next generation botulinum toxin and small molecule toxin substitutes
○ 주요 연구논문(Major Research Achievements)
▪ Endocytosing Escherichia coli as a whole-cell biocatalyst of fatty acids. ACS Synthetic Biology. 2019
▪ Virucidal nano-perforator of viral membrane trapping viral RNAs in the endosome. Nature Communications. 2019
▪ SNARE- Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation. Frontiers in Immunology. 2018
▪ Engineering of -1,3-fucosyltransferases for production of 3-fucosyllactose in Escherichia coli. Metabolic Engineering, 2018
▪ A chemical controller of SNARE-driven membrane fusion that primes vesicles for Ca2+-triggered millisecond exocytosis, Journal of the American Chemical Society, 2016
○ 연구협력 필요 분야(Research Interest)
▪ We developed a neuron-specific delivery system and want to find useful applications of this technology.
▪ Antiviral effect of nanoperforator for various enveloped viruses.
○ 연구협력 가능 분야(Research Collaboration)
▪ Potential protein vaccines which are hard to express, thus hardly immunogenic, because they are membrane-bound proteins
▪ Nanodisc technologies
▪ Engineering proteins with improved solubility and stability