○ Experience
1995 Ph.D. Neuropharmacology, Chungbuk National University
2001 - Present : Sungkyunkwan University, School of Pharmacy, Professor
2009 - 2010 : The Scripps Research Institute, Visiting Professor
2000 - 2001 : Hallym University, School of Medicine, Research Professor
1996 - 2000 : University of Mississippi Medical Center, Research Associate
○ Major Research Achievements
· Kwon SH, Ma SX, Hong SI, Lee SY, Jang CG. Lonicera japonica THUNB. Extract Inhibits Lipopolysaccharide-Stimulated Inflammatory Responses by Suppressing NF-κB Signaling in BV-2 Microglial Cells. J Med Food. 2015 Apr 21. [Epub ahead of print], 2015
· Kwon SH, Hong SI, Ma SX, Lee SY, Jang CG. 3',4',7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress. Food Chem Toxicol. 2015 Jun;80:41-51. doi:10.1016/j.fct.2015.02.014. Epub 2015 Feb 23., 2015
· Jung YH, Hong SI, Ma SX, Hwang JY, Kim JS, Lee JH, Seo JY, Lee SY, Jang CG. Strain differences in the chronic mild stress animal model of depression and anxiety in mice. Biomol Ther (Seoul). 2014 Sep;22(5):453-9. doi: 0.4062/biomolther.2014.058. Epub 2014 Sep 30., 2014
· Kwon SH, Ma SX, Lee SY, Jang CG. Sulfuretin inhibits 6-hydroxydopamine-induced neuronal cell death via reactive oxygen species-dependent mechanisms in human neuroblastoma SH-SY5Y cells. Neurochem Int. 2014 Jul;74:53-64. doi: 10.1016/j.neuint.2014.04.016. Epub 2014 May 4., 2014
· Nguyen TL, Kwon SH, Hong SI, Ma SX, Jung YH, Hwang JY, Kim HC, Lee SY, Jang CG. Transient receptor potential vanilloid type 1 channel may modulate opioid reward. Neuropsychopharmacology. 2014 Sep;39(10):2414-22. doi: 10.1038/npp.2014.90. Epub 2014 Apr 15., 2014
· Kwon SH, Ma SX, Hong SI, Kim SY, Lee SY, Jang CG. Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells. J Ethnopharmacol. 2014 Feb 27;152(1):173-82. doi: 10.1016/j.jep.2013.12.048. Epub 2014 Jan 15., 2014
○ Research Interest
· 필로폰 등 약물남용 기전 및 치료제 개발
· 정신신경계 질환 (우울증, 불안, 치매 등) 제어 기술
· 신종 유사 마약류의 의존성 평가